10 Facts about BRCA Gene

Tuesday, August 25th 2015. | Medical

Facts about BRCA Gene talk about the human gene. BRCA1 is considered as the caretaker gene that can be found in all humans.  The scientists also define BRCA1 as the human tumor suppressor gene. The breast and other tissues are the common place to find out BRCA1 and BRCA2. If the DNA cannot be repaired in those tissues, the gene will destroy the cells or damage DNA. Here are other interesting facts about BRCA Gene:

Facts about BRCA Gene 1: the chromosomal damage

In the chromosomal damage, the BCRA1 is involved to fix it. If there is a BCRA mutation which damages BCRA 1 or BCRA 2, it means the proper repair is not conducted on the damaged DNA. It can enhance the risk of having breast cancer.

Facts about BRCA Gene 2: the terms

Many people call BCRA1 and BCRA2 as the breast cancer susceptible protein or the breast cancer susceptible gene. Actually both genes are normal. What makes them abnormal is the BCRA mutation.

Facts about BRCA Gene

Facts about BRCA Gene

Facts about BRCA Gene 3: BASC

BASC stands for BRCA1-associated genome surveillance complex. It is the multi subunit protein complex formed by the combination of BCRA1 with signal transducers, DNA damage sensors, and tumor suppressors.

Facts about BRCA Gene 4: Myriad Genetics

Myriad Genetics has the patent for the method used to diagnose the risk of having cancer on the patients who have BCRA1 or BCRA2 mutations.



Facts about BRCA Gene 5: Myriad’s revenue

In 2012, Myriad earned the annual revenue around $500M. It also had around 1200 workers. The company was established in 1994 and provided the people for diagnostic test of cancer. The price for the diagnostic test is very expensive and it earns criticism.

Facts about BRCA Gene 6: the existence of BCRA1

In 1990, King Laboratory at UC Berkeley provided the first evidence that BCRA1 exists. Find out facts about brain tumors here.

BRCA Gene Picture

BRCA Gene Picture

Facts about BRCA Gene 7: the cloned of the gene

The scientists at University of Utah, NIEHS and Myriad Generics were able to clone the BCRA1 gene in 1994.

Facts about BRCA Gene 8: BRCA2

BRCA2 is called as the human tumor suppressor gene. This gene can be found in human and most mammals.

BRCA Gene Image

BRCA Gene Image

Facts about BRCA Gene 9: BCRA mutations

BCRA1 and BCRA2 are very susceptible to mutations. The scientists have identified different kinds of mutations on the genes. Some of them are harmful.

Facts about BRCA Gene 10: the breast cancer

The mutation on BCRA1 is more common than the mutation found in BCRA2. The breast cancer cases caused by BCRA1 or BCRA 2 only occupies 5 to 10 percent of the whole cases. Get facts about breast cancer here.

BRCA Gene Facts

BRCA Gene Facts

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