10 Facts about Acetylcholine
Facts about Acetylcholine present the detail scientific idea about an organic molecule that you can find inside human being and other organisms. Inside the body, the molecule acts as the neurotransmitter. If you are interested to learn about Acetylcholine, get more facts below:
Facts about Acetylcholine 1: Henry Hallett Dale
Henry Hallett Dale was the first scientist who identified Acetylcholine or ACh in 1915. He did an action on a heart tissue. ACh is called as the first identified neurotransmitter in the world of Science.
Facts about Acetylcholine 2: Otto Loewi
The one who confirmed that ACh is a neurotransmitter was Otto Loewi. At first, he calls this chemical as Vagusstoff. The name was derived from the vagus nerve for it was released from the nerve. Due to their wonderful work on ACh, both Loewi and Dale received a Nobel Prize in 1936.
Facts about Acetylcholine 3: function
Let’s find out the function of ACh. The main function is as a neuromodulator in the central nervous system and peripheral nervous system.
Facts about Acetylcholine 4: the peripheral nervous system
ACh can activate the muscles in the peripheral nervous system. We call it as the primary neurotransmitter in autonomic nervous system. Find out another chemical in acetic acid facts.
Facts about Acetylcholine 5: acetylcholine receptor
Acetylcholine receptor is abbreviated AChR. You can find two primary classes for AChR. Both are muscarinic acetylcholine receptors and nictoinic acetylcholine receptors.
Facts about Acetylcholine 6: treatment of disease
The diseases such as Alzheimer and myasthenia gravis are treated by using ACh Receptor Agonists. The common drug used in the Alzheimer treatment is galantamine hydrobromide which can inhibit acetylcholinesterase.
Facts about Acetylcholine 7: result of the treatment
When the patients with Alzheimer disease consume the drugs which inhibit enzyme acetylcholinesterase, it can bring continuous stimulation of the central nervous system, glands and muscles.
Facts about Acetylcholine 8: acetylcholine levels
The level of acetylcholine can be increased when the patients consume the drugs which inhibit enzyme acetylcholinesterase. They include Huperzine A, Donepezil, Rivastigmine, Neostigmine and Pyridostigmine.
Facts about Acetylcholine 9: acetylcholine deficiency
Acetylcholine deficiency can occur in the body if you consume methylmercury and other organic mercurial compounds.
Facts about Acetylcholine 10: Chemical syntheses
Acetylcholine can be synthesized in various ways. You can react 2-chloroethanol acetate with trimethylamine. If you want to know about another synthesis, get facts about acids and bases here.
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